Wednesday 28 February 2024
Salisbury Foundation Trust

FOI_7296

Internal Reference Number: FOI_7296

Date Request Received: 11/07/2023 00:00:00

Date Request Replied To: 02/08/2023 00:00:00

This response was sent via: By Email

Request Summary: Oesophageal and Gastric Cancer

Request Category: Companies

 
Question Number 1:
How many patients were treated in the past 3 months for gastric and gastro-oesophageal junction cancer (any stage) with:

• CAPOX (Capecitabine with Oxaliplatin)

• FOLFOX (Folinic acid, Fluorouracil and Oxaliplatin)

• Lonsurf (Trifluridine - tipiracil)

• Nivolumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidine (5-Fluorouracil or Capecitabine)

• Pembrolizumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidine (5-Fluorouracil or Capecitabine)

• Any other systemic anti-cancer therapy

• Palliative care only
 
Answer To Question 1:
• CAPOX (Capecitabine with Oxaliplatin) <5

• FOLFOX (Folinic acid, Fluorouracil and Oxaliplatin) 0

• Lonsurf (Trifluridine - tipiracil) 0

• Nivolumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidine (5-Fluorouracil or Capecitabine) 0

• Pembrolizumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidine (5-Fluorouracil or Capecitabine) 0

• Any other systemic anti-cancer therapy <5

• Palliative care only unable to answer
 
Question Number 2:
How many patients were treated in the past 3 months for Oesophageal cancer (any stage) with:

• Nivolumab monotherapy or combination with Ipilimumab

• Nivolumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine)

• Pembrolizumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine)

• Platinum and Fluoropyrimidene based combination treatments (Cisplatin or Oxaliplatin with 5-Fluorouracil or Capecitabine)

• Any other systemic anti-cancer therapy

• Palliative care only
 
Answer To Question 2:
• Nivolumab monotherapy or combination with Ipilimumab 1

• Nivolumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine) 0

• Pembrolizumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine) 0

• Platinum and Fluoropyrimidene based combination treatments (Cisplatin or Oxaliplatin with 5-Fluorouracil or Capecitabine) <5

• Any other systemic anti-cancer therapy <5

• Palliative care only unable to answer
 
Question Number 3:
How many patients were treated in the past 3 months for advanced/metastatic resected oesophageal cancer ONLY with:

• Nivolumab monotherapy or combination with Ipilimumab

• Nivolumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine)

• Pembrolizumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine)

• Platinum and Fluoropyrimidene based combination treatments (Cisplatin or Oxaliplatin with 5-Fluorouracil or Capecitabine)

• Any other systemic anti-cancer therapy

• Palliative care only


 
Answer To Question 3:
Nivolumab monotherapy or combination with Ipilimumab 0

• Nivolumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine) 0

• Pembrolizumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine) 0

• Platinum and Fluoropyrimidene based combination treatments (Cisplatin or Oxaliplatin with 5-Fluorouracil or Capecitabine) 0

• Any other systemic anti-cancer therapy <5

Palliative care only unable to answer
 
Question Number 4:
In the past 3 months, how many patients have been initiated* on the following agents for treatment for gastric, gastro-oesophageal junction or Oesophageal cancer:

• Nivolumab monotherapy or in combination with Ipilimumab

• Nivolumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine)

• Pembrolizumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine)

*Patients are considered initiated if they have not been treated in the previous 6 months with any of the drugs that are part of the named regimen.
 
Answer To Question 4:
• Nivolumab monotherapy or in combination with Ipilimumab <5

• Nivolumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine) 0

• Pembrolizumab in combination with Platinum (Cisplatin or Oxaliplatin) and Fluoropyrimidene (5-Fluorouracil or Capecitabine) 0

*Patients are considered initiated if they have not been treated in the previous 6 months with any of the drugs that are part of the named regimen.
 
Question Number 5:
Does your trust participate in any clinical trials for gastric cancer? If so, please provide the name of each trial and the number of patients taking part.
 
Answer To Question 5:
The Trust is not currently participating in any clinical trials for gastric cancer.
 
Question Number 6:
Does your trust participate in any clinical trials for oesophageal cancer? If so, please provide the name of each trial and the number of patients taking part.
 
Answer To Question 6:
The Trust is not currently participating in any clinical trials for oesophageal cancer.
 
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